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ECCN reference · Category 1: Special materials and related equipment, chemicals, microorganisms and toxins

ECCN 1C351

Human and animal pathogens and "toxins," as follows

Materials. Reasons for control: CB (Chemical and biological weapons), CW (Chemical Weapons Convention), AT (Anti-terrorism).

Does 1C351 need a license to your country?

Enter the full classification (for example 1C351.a.1) and a destination. The check reads the Country Chart, the end-use and embargo rules, and shows the rule and source behind the answer.

License requirement check

Item classification and destination. No account needed.

An ECCN (such as 5A992.c) is an exact match and works best. Word search matches the official CCL wording and a reviewed list of everyday names as you write them; it does not guess what you mean or fix spelling. Don’t know the ECCN? Use Find the ECCN.

License requirements

Each control below comes from the entry’s License Requirements table. Where it names a Country Chart column, the countries with an X in that column need a license for the items the control covers, unless a License Exception applies.

  • CB (Chemical and biological weapons): CB applies to items controlled by 1C351.d.15 and .16.
    Country Chart column CB1: a license is needed to 196 countries with an X

    Afghanistan, Albania, Algeria, Andorra, Angola, Antigua and Barbuda, Argentina, Armenia, Aruba, Australia, Austria, Azerbaijan, Bahamas, The, Bahrain, Bangladesh, Barbados, Belarus, Belgium, Belize, Benin, Bhutan, Bolivia, Bosnia and Herzegovina, Botswana, Brazil, Brunei, Bulgaria, Burkina Faso, Burma, Burundi, Cambodia, Cameroon, Canada, Cape Verde, Central African Republic, Chad, Chile, China, Colombia, Comoros, Congo (Democratic Republic of the), Congo (Republic of the), Costa Rica, Cote d'Ivoire, Croatia, Curaçao, Cyprus, Czech Republic, Denmark, Djibouti, Dominica, Dominican Republic, Ecuador, Egypt, El Salvador, Equatorial Guinea, Eritrea, Estonia, Eswatini, Ethiopia, Fiji, Finland, France, Gabon, Gambia, The, Georgia, Germany, Ghana, Greece, Grenada, Guatemala, Guinea, Guinea-Bissau, Guyana, Haiti, Honduras, Hungary, Iceland, India, Indonesia, Iraq, Ireland, Israel, Italy, Jamaica, Japan, Jordan, Kazakhstan, Kenya, Kiribati, Korea, South, Kosovo, Kuwait, Kyrgyzstan, Laos, Latvia, Lebanon, Lesotho, Liberia, Libya, Liechtenstein, Lithuania, Luxembourg, Macau, Madagascar, Malawi, Malaysia, Maldives, Mali, Malta, Marshall Islands, Mauritania, Mauritius, Mexico, Micronesia (Federated State of), Moldova, Monaco, Mongolia, Montenegro, Morocco, Mozambique, Namibia, Nauru, Nepal, Netherlands, New Zealand, Nicaragua, Niger, Nigeria, North Macedonia, Norway, Oman, Pakistan, Palau, Panama, Papua New Guinea, Paraguay, Peru, Philippines, Poland, Portugal, Qatar, Romania, Russia, Rwanda, Samoa, San Marino, Sao Tome and Principe, Saudi Arabia, Senegal, Serbia, Seychelles, Sierra Leone, Singapore, Sint Maarten (the Dutch two-fifths of the island of Saint Martin), Slovakia, Slovenia, Solomon Islands, Somalia, South Africa, South Sudan, Republic of, Spain, Sri Lanka, St. Kitts and Nevis, St. Lucia, St. Vincent and the Grenadines, Sudan, Suriname, Sweden, Switzerland, Taiwan, Tajikistan, Tanzania, Thailand, Timor-Leste, Togo, Tonga, Trinidad and Tobago, Tunisia, Turkmenistan, Tuvalu, Türkiye, Uganda, Ukraine, United Arab Emirates, United Kingdom, Uruguay, Uzbekistan, Vanuatu, Vatican City, Venezuela, Vietnam, Western Sahara, Yemen, Zambia, Zimbabwe.

  • CB (Chemical and biological weapons): CB applies to entire entry.
    Country Chart column CB2: a license is needed to 154 countries with an X

    Afghanistan, Albania, Algeria, Andorra, Angola, Antigua and Barbuda, Armenia, Aruba, Azerbaijan, Bahamas, The, Bahrain, Bangladesh, Barbados, Belarus, Belize, Benin, Bhutan, Bolivia, Bosnia and Herzegovina, Botswana, Brazil, Brunei, Burkina Faso, Burma, Burundi, Cambodia, Cameroon, Cape Verde, Central African Republic, Chad, Chile, China, Colombia, Comoros, Congo (Democratic Republic of the), Congo (Republic of the), Costa Rica, Cote d'Ivoire, Curaçao, Djibouti, Dominica, Dominican Republic, Ecuador, Egypt, El Salvador, Equatorial Guinea, Eritrea, Eswatini, Ethiopia, Fiji, Gabon, Gambia, The, Georgia, Ghana, Grenada, Guatemala, Guinea, Guinea-Bissau, Guyana, Haiti, Honduras, Indonesia, Iraq, Israel, Jamaica, Jordan, Kazakhstan, Kenya, Kiribati, Kosovo, Kuwait, Kyrgyzstan, Laos, Lebanon, Lesotho, Liberia, Libya, Macau, Madagascar, Malawi, Malaysia, Maldives, Mali, Marshall Islands, Mauritania, Mauritius, Micronesia (Federated State of), Moldova, Monaco, Mongolia, Montenegro, Morocco, Mozambique, Namibia, Nauru, Nepal, Nicaragua, Niger, Nigeria, North Macedonia, Oman, Pakistan, Palau, Panama, Papua New Guinea, Paraguay, Peru, Philippines, Qatar, Russia, Rwanda, Samoa, San Marino, Sao Tome and Principe, Saudi Arabia, Senegal, Serbia, Seychelles, Sierra Leone, Singapore, Sint Maarten (the Dutch two-fifths of the island of Saint Martin), Solomon Islands, Somalia, South Africa, South Sudan, Republic of, Sri Lanka, St. Kitts and Nevis, St. Lucia, St. Vincent and the Grenadines, Sudan, Suriname, Taiwan, Tajikistan, Tanzania, Thailand, Timor-Leste, Togo, Tonga, Trinidad and Tobago, Tunisia, Turkmenistan, Tuvalu, Uganda, United Arab Emirates, Uruguay, Uzbekistan, Vanuatu, Vatican City, Venezuela, Vietnam, Western Sahara, Yemen, Zambia, Zimbabwe.

  • AT (Anti-terrorism): AT applies to entire entry. No Country Chart country has an X in column AT1; the destinations this control targets are under “Not decided by the Country Chart” below. The entry adds: Column 1.
  • CW (Chemical Weapons Convention): CW applies to 1C351.d.15 and .d.16 and a license is required for CW reasons for all destinations, including Australia, Canada, and the United Kingdom, as follows: CW applies to 1C351.d.15 for ricin in the form of (1) Ricinus communis AgglutininII (RCA_(II)), also known as ricin D or Ricinus Communis LectinIII (RCL_(III)) and (2) Ricinus communis LectinIV (RCL_(IV)), also known as ricin E. CW applies to 1C351.d.16 for saxitoxin identified by C.A.S. #35523-89-8. See § 742.18 of the EAR for licensing information pertaining to chemicals subject to restriction pursuant to the Chemical Weapons Convention (CWC). The Commerce Country Chart is not designed to determine licensing requirements for items controlled for CW reasons. CW applies to 1C351.d.15 and .d.16 and a license is required for CW reasons for all destinations, including Australia, Canada, and the United Kingdom, as follows: CW applies to 1C351.d.15 for ricin in the form of (1) Ricinus communis AgglutininII (RCA_(II)), also known as ricin D or Ricinus Communis LectinIII (RCL_(III)) and (2) Ricinus communis LectinIV (RCL_(IV)), also known as ricin E. CW applies to 1C351.d.16 for saxitoxin identified by C.A.S. #35523-89-8. See § 742.18 of the EAR for licensing information pertaining to chemicals subject to restriction pursuant to the Chemical Weapons Convention (CWC). The Commerce Country Chart is not designed to determine licensing requirements for items controlled for CW reasons.

Not decided by the Country Chart: Covered Donetsk region of Ukraine (DNR), Covered Luhansk region of Ukraine (LNR), Crimea region of Ukraine, Cuba, Iran, Korea, North, Syria. These destinations are under embargoes or other special controls in 15 CFR Part 746, which require a license for most items whatever the chart shows. Russia and Belarus also have broad Part 746 controls in addition to the chart.

A blank on the Country Chart is not permission to ship. End-use and end-user rules (15 CFR Part 744), embargoes and sanctions (Part 746), and the parties to the transaction still apply. Use the check above for your item and country.

List-based License Exceptions

As the entry lists them. Each exception has its own conditions in 15 CFR Part 740, and § 740.2 bars or limits most of them for Russia, Belarus, Country Group D:5 and embargoed destinations, so an entry’s “Yes” does not mean it is available everywhere.

  • LVS: N/A
  • GBS: N/A

Items in 1C351

The controls often apply to some paragraphs only, so check the full paragraph, for example 1C351.a.

Show all 112 paragraphs
  • 1C351.a Viruses identified on the Australia Group (AG) "List of Human and Animal Pathogens and Toxins for Export Control," as follows:
  • 1C351.a.1 African horse sickness virus;
  • 1C351.a.2 African swine fever virus;
  • 1C351.a.3 Andes virus;
  • 1C351.a.4 Avian influenza (AI) viruses identified as having high pathogenicity (HP), as follows:
  • 1C351.a.4.a AI viruses that have an intravenous pathogenicity index (IVPI) in 6-week-old chickens greater than 1.2; or
  • 1C351.a.4.b AI viruses that cause at least 75% mortality in 4- to 8-week-old chickens infected intravenously.
  • 1C351.a.5 Bluetongue virus;
  • 1C351.a.6 Chapare virus;
  • 1C351.a.7 Chikungunya virus;
  • 1C351.a.8 Choclo virus;
  • 1C351.a.9 Classical swine fever virus (Hog cholera virus);
  • 1C351.a.10 Crimean-Congo hemorrhagic fever virus;
  • 1C351.a.11 Dobrava-Belgrade virus;
  • 1C351.a.12 Eastern equine encephalitis virus;
  • 1C351.a.13 Ebolavirus (includes all members of the Ebolavirus genus);
  • 1C351.a.14 Foot-and-mouth disease virus;
  • 1C351.a.15 Goatpox virus;
  • 1C351.a.16 Guanarito virus;
  • 1C351.a.17 Hantaan virus;
  • 1C351.a.18 Hendra virus (Equine morbillivirus);
  • 1C351.a.19 Japanese encephalitis virus;
  • 1C351.a.20 Junin virus;
  • 1C351.a.21 Kyasanur Forest disease virus;
  • 1C351.a.22 Laguna Negra virus;
  • 1C351.a.23 Lassa virus;
  • 1C351.a.24 Louping ill virus;
  • 1C351.a.25 Lujo virus;
  • 1C351.a.26 Lumpy skin disease virus;
  • 1C351.a.27 Lymphocytic choriomeningitis virus;
  • 1C351.a.28 Machupo virus;
  • 1C351.a.29 Marburgvirus (includes all members of the Marburgvirus genus);
  • 1C351.a.30 Middle East respiratory syndrome-related coronavirus (MERS-related coronavirus);
  • 1C351.a.31 Monkeypox virus;
  • 1C351.a.32 Murray Valley encephalitis virus;
  • 1C351.a.33 Newcastle disease virus;
  • 1C351.a.34 Nipah virus;
  • 1C351.a.35 Omsk hemorrhagic fever virus;
  • 1C351.a.36 Oropouche virus;
  • 1C351.a.37 Peste-des-petits ruminants virus;
  • 1C351.a.38 Porcine Teschovirus;
  • 1C351.a.39 Powassan virus;
  • 1C351.a.40 Rabies virus and all other members of the Lyssavirus genus;
  • 1C351.a.41 Reconstructed 1918 influenza virus;
  • 1C351.a.42 Rift Valley fever virus;
  • 1C351.a.43 Rinderpest virus;
  • 1C351.a.44 Rocio virus;
  • 1C351.a.45 Sabia virus;
  • 1C351.a.46 Seoul virus;
  • 1C351.a.47 Severe acute respiratory syndrome-related coronavirus (SARS-related coronavirus);
  • 1C351.a.48 Sheeppox virus;
  • 1C351.a.49 Sin Nombre virus;
  • 1C351.a.50 St. Louis encephalitis virus;
  • 1C351.a.51 Suid herpesvirus 1 (Pseudorabies virus; Aujeszky's disease);
  • 1C351.a.52 Swine vesicular disease virus;
  • 1C351.a.53 Tick-borne encephalitis virus (Far Eastern subtype, formerly known as Russian Spring-Summer encephalitis virus-see 1C351.b.3 for Siberian subtype);
  • 1C351.a.54 Variola virus;
  • 1C351.a.55 Venezuelan equine encephalitis virus;
  • 1C351.a.56 Vesicular stomatitis virus;
  • 1C351.a.57 Western equine encephalitis virus; or
  • 1C351.a.58 Yellow fever virus.
  • 1C351.b Viruses identified on the APHIS/CDC "select agents" lists (see Related Controls paragraph #2 for this ECCN), but not identified on the Australia Group (AG) "List of Human and Animal Pathogens and Toxins for Export Control," as follows:
  • 1C351.b.3 Tick-borne encephalitis virus (Siberian subtype, formerly West Siberian virus-see 1C351.a.53 for Far Eastern subtype).
  • 1C351.c Bacteria identified on the Australia Group (AG) "List of Human and Animal Pathogens and Toxins for Export Control," as follows:
  • 1C351.c.1 Bacillus anthracis;
  • 1C351.c.2 Brucella abortus;
  • 1C351.c.3 Brucella melitensis;
  • 1C351.c.4 Brucella suis;
  • 1C351.c.5 Burkholderia mallei (Pseudomonas mallei);
  • 1C351.c.6 Burkholderia pseudomallei (Pseudomonas pseudomallei);
  • 1C351.c.7 Chlamydia psittaci (Chlamydophila psittaci);
  • 1C351.c.8 Clostriduim argentinense (formerly known as Clostridium botulinum Type G), botulinum neurotoxin producing strains;
  • 1C351.c.9 Clostridium baratii, botulinum neurotoxin producing strains;
  • 1C351.c.10 Clostridium botulinum;
  • 1C351.c.11 Clostridium butyricum, botulinum neurotoxin producing strains;
  • 1C351.c.12 Clostridium perfringens, epsilon toxin producing types;
  • 1C351.c.13 Coxiella burnetii;
  • 1C351.c.14 Francisella tularensis;
  • 1C351.c.15 Mycoplasma capricolum subspecies capripneumoniae ("strain F38");
  • 1C351.c.16 Mycoplasma mycoides subspecies mycoides SC (small colony) (a.k.a. contagious bovine pleuropneumonia);
  • 1C351.c.17 Rickettsia prowazekii;
  • 1C351.c.18 Salmonella enterica subspecies enterica serovar Typhi (Salmonella typhi);
  • 1C351.c.19 Shiga toxin producing Escherichia coli (STEC) of serogroups O26, O45, O103, O104, O111, O121, O145, O157, and other shiga toxin producing serogroups;
  • 1C351.c.20 Shigella dysenteriae;
  • 1C351.c.21 Vibrio cholerae; or
  • 1C351.c.22 Yersinia pestis.
  • 1C351.d "Toxins" identified on the Australia Group (AG) "List of Human and Animal Pathogens and Toxins for Export Control," as follows, or their subunits:
  • 1C351.d.1 Abrin;
  • 1C351.d.2 Aflatoxins;
  • 1C351.d.3 Botulinum neurotoxins;
  • 1C351.d.4 Brevetoxins;
  • 1C351.d.5 Clostridium perfringens alpha, beta 1, beta 2, epsilon and iota toxins;
  • 1C351.d.6 Conotoxins;
  • 1C351.d.7 Diacetoxyscirpenol;
  • 1C351.d.8 Gonyautoxins;
  • 1C351.d.9 HT-2 toxin;
  • 1C351.d.10 Microcystins (Cyanginosins);
  • 1C351.d.11 Modeccin;
  • 1C351.d.12 Neosaxitoxin (NEO);
  • 1C351.d.13 Nodularins;
  • 1C351.d.14 Palytoxin;
  • 1C351.d.15 Ricin;
  • 1C351.d.16 Saxitoxin;
  • 1C351.d.17 Shiga toxins (shiga-like toxins, verotoxins, and verocytotoxins);
  • 1C351.d.18 Staphylococcus aureus enterotoxins, hemolysin alpha toxin, and toxic shock syndrome toxin (formerly known as Staphylococcus enterotoxin F);
  • 1C351.d.19 T-2 toxin;
  • 1C351.d.20 Tetrodotoxin;
  • 1C351.d.21 Viscumin (Viscum album lectin 1); or
  • 1C351.d.22 Volkensin.
  • 1C351.e "Fungi", as follows:
  • 1C351.e.1 Coccidioides immitis; or
  • 1C351.e.2 Coccidioides posadasii.

Source

Commerce Control List, 15 CFR Part 774, Supplement No. 1 (official text on eCFR), as of August 21, 2026, 1:45AM EDT. Commerce Country Chart, Supplement No. 1 to Part 738, as of August 21, 2026, 1:45AM EDT.

This page is a preliminary reference, not legal advice, a classification ruling or permission to ship. Confirm the classification against the full official text.